Vayne has 12 skins (13 including classic). The most recent one was released on 22 July 2020.
| Name | RP | ReleaseDate | Chromas? | Legacy? | Special? |
|---|---|---|---|---|---|
 Spirit Blossom Vayne | 1350 | 2020-07-22 | |||
 FPX Vayne | 1350 | 2020-04-30 | |||
 Firecracker Vayne Prestige Edition | 2019-01-28 | ||||
 Firecracker Vayne | 1350 | 2019-01-28 | |||
 PROJECT Vayne | 1820 | 2017-11-22 | |||
 Soulstealer Vayne | 2016-06-29 | ||||
 Arclight Vayne | 975 | 2015-04-21 | |||
 SKT T1 Vayne | 750 | 2014-05-05 | |||
 Heartseeker Vayne | 975 | 2012-02-14 | |||
 Dragonslayer Vayne | 975 | 2011-08-24 | |||
 Vindicator Vayne | 520 | 2011-05-10 | |||
 Aristocrat Vayne | 520 | 2011-05-10 |